Meghan Lybecker, Ph.D.

Meghan Lybecker, Ph.D.

Meghan Lybecker, Ph.D.

Assistant Professor
UCCS Biology Department

OCSE B345; laboratory OSCE B404

Education

  • 2011-2014 Postdoc, Department of Biochemistry and Cell Biology, University of Vienna, Max F. Perutz Laboratories, Vienna, Austria
  • 2007-2010 Postdoc, Division of Biological Sciences, University of Montana, Missoula, MT
  • 2007  Ph.D. Integrated Biochemistry/Microbiology, University of Montana, Missoula, MT
  • 1999 B.S. Biology,  Eastern Oregon University, La Grande, OR

Research Interests

All organisms must sense and adapt to environmental pressures by regulating their gene expression. I am interested in understanding the molecular mechanisms that bacteria employ to regulate gene expression in response to changing environmental conditions. RNA has emerged as one of the key players in gene regulation in both prokaryotes and eukaryotes. My primary research focus is on non-coding RNA molecular mechanisms of gene regulation in Borrelia burgdorferi (the causative agent of Lyme disease), at the bacteria/host interface, and in the model organism Escherichia coli.

Selected Publications:

  • Lybecker M, Zimmermann B, Bilusic I, Tukhtubaeva N and Schroeder R. (2014) The double-stranded transcriptome of Escherichia coli. PNAS 111(8):3134-9.
  • Bilusic I, Popitsch N, Rescheneder P, Schroeder R and Lybecker M. (2014) Revisiting the coding potential of the E. coli genome through Hfq co-immunoprecipitation. RNA Biology 11(5)
  • Lybecker M, Bilusic I and Raghavan R. (2014) Pervasive Transcription: detecting functional RNAs in bacteria. Transcription In press
  • Lybecker, M.C., Abel, C.A., Feig, A.L., and Samuels, D.S. (2010) Identification and function of the RNA chaperone Hfq in the Lyme disease spirochete Borrelia burgdorferi. Mol. Micorbiol. 78: 622-63.
  • Lybecker, M.C., and Samuels, D.S. (2007) Temperature-induced regulation of RpoS by a small RNA in Borrelia burgdorferi. Mol. Microbiol. 64: 1075-89.

Courses Taught

  • BIOL 1350 General Biology: Intro to the Cell
  • BIOL 3020 Cell Biology
  • BIOL 3100 Microbiology - Bacteriology/Mycology
  • BIOL 3110 Bacteriology Lab